Luis Castillo faces Schwarber in a high-profile clash. Castillo’s 2025 numbers include HR susceptibility at times, and Schwarber’s career success against Castillo adds intrigue to the +200 line. Castillo’s ability to limit damage will be the determinant for Schwarber’s odds to homer.

Castillo draws a tough assignment vs Philly’s lineup, with a homer-prone profile that needs to be contained. His 3.48 ERA belies the homer risk, especially against a power-heavy PHI squad that has shown late-season momentum. The road environment adds another layer for fantasy managers weighing cash versus GPP exposure.

Castillo draws a marquee start against Luzardo in a pivotal series finale, giving Seattle a chance to slow Philadelphia’s order. His 3.48 ERA and 8-6 record underscore his role as a frontline weapon in a hotly contested stretch run.

Castillo opened the game for Seattle, facing Lindor’s early offense and then stepping into a mid-innings duel as Mets surged. He worked as Seattle’s setup for a bullpen-heavy night, providing quality innings and holding the Mets at bay before the late rally.

Castillo headlines the matchup with elite strikeout potential and a floor built on per-start velocity and swing-and-miss rates. His matchup vs Manaea provides a ceiling for double-digit K games, and his recent form supports a top-tier fantasy ace play in daily formats.